Hydrolyzable delivery system using crosslinked polymeric resins

Details Hydrolyzable delivery system using crosslinked polymeric resins Hydrolyzable delivery system using crosslinked polymeric resins

1998-03-30

2000-08-01

Wu, David W.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

424 7818, 424 7827, 424179, 424449, C08C 912, C08C 1924, A61K 3174, A61K 39395, A61F 1300

Patent

active

060968346

ABSTRACT:
This invention provides a method of preparing a polymeric delivery system for active ingredients. The delivery system is formed either by attaching the active ingredient to a linker through a hydrolyzable covalent bond, then forming a covalent bond between the linker and a portion of the subunits of a crosslinked polymer, or by attaching a linker to a portion of the subunits of a crosslinked polymer, then attaching the active ingredient to the polymer-linker combination through a hydrolyzable covalent bond. The invention also provides a delivery system comprising an active ingredient covalently bonded through a hydrolyzable covalent bond to a linker, which is in turn covalently bonded to a portion of subunits of a crosslinked polymer.

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