Hydrolytic kinetic resolution of cyclic substrates

Details Hydrolytic kinetic resolution of cyclic substrates Hydrolytic kinetic resolution of cyclic substrates

2007-05-22

2007-05-22

McKane, Joseph K. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S513000, C548S954000

Reexamination Certificate

active

11029887

ABSTRACT:
The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.

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