Hydroisoindoline tachykinin receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S512000

Reexamination Certificate

active

07345083

ABSTRACT:
The present invention is directed to certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.

REFERENCES:
patent: WO 97/141671 (1997-04-01), None
patent: WO 2005/032464 (2005-04-01), None
Co-pending U.S. Appl. No. 10/586,727, filed Jul. 18, 2006.

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