Hydrogenation process for the preparation of 5,6 cis- and 5,6-tr

Details Hydrogenation process for the preparation of 5,6 cis- and 5,6-tr Hydrogenation process for the preparation of 5,6 cis- and 5,6-tr

1977-05-31

1979-06-26

Love, Ethel G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2603972, A61K 3159

Patent

active

041593260

ABSTRACT:
A process for the preparation of 5,6-cis- and 5,6-trans-10,19-dihydro-vitamin D derivatives which comprises hydrogenating a corresponding vitamin D compound in the presence of a ligand-coordinated homogeneous transition metal catalyst whereby the C-19 methylene group of the vitamin D compound is converted into a methyl group.

REFERENCES:
patent: 2942009 (1960-06-01), Westerhof
patent: 3049553 (1962-08-01), Schenck
patent: 3607888 (1971-09-01), DeLuca et al.
patent: 3697559 (1972-10-01), DeLuca et al.
patent: 3725489 (1973-04-01), Fuhrmann et al.
patent: 4011250 (1977-03-01), Ishikawa

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