Hydrogen peroxide based ECL

Details Hydrogen peroxide based ECL Hydrogen peroxide based ECL

1995-06-07

2000-08-08

Tucker, Philip

Compositions

Chemiluminescent

435 4, 435 5, 435 6, 252583, 2524081, 436805, C09K 300, C12Q 100, G02F 100

Patent

active

060997605

ABSTRACT:
An electrochemiluminescence (ECL)-based assay for the quantitation of classical clinical chemistry analytes, where glucose, ethanol, carbon dioxide, cholesterol, as H.sub.2 O.sub.2 liberating systems coupled to a tris(bipyridyl)ruthenium(II) Ru(bpy).sub.3.sup.2+ luminophore generate an ECL signal, which can be detected spectrophotometrically or electrochemically. The H.sub.2 O.sub.2 present reacts with oxalate in the presence of Ru(bpy).sub.3.sup.2+ to give an ECL response.

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