Hydrogels of quadrol methacrylate polymers

Details Hydrogels of quadrol methacrylate polymers Hydrogels of quadrol methacrylate polymers

1986-10-06

1988-11-01

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Lymphokine

524555, 526312, A61K 3178, C08L 3900

Patent

active

047819219

ABSTRACT:
Acrylate and methacrylate monoesters and diesters having the following formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 are as defined in the specification, are disclosed. These monomers are polymerizable into hydrogel polymers which are extremely hydrophilic. These hydrogel polymers are useful in the preparation of wound dressings. These polymers form complexes with polyvalent metal ions such as Ca, Mg, Mn and Cu, and possess macrophage stimulating activity in addition to the useful properties possessed by other acrylate and methacrylate hydrogel polymers.

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Smith et al., Journal of Poly. Letters, vol. 23, pp. 633-637, Jul. 1, 1985.
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Kickhoefen, B. et al., Biomaterials, vol. 7, pp. 67-72, (1986).
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Refojo, M. F. et al., Journal of Applied Polymer Science, vol. 9, pp. 2425-2435, 3161-3170, (1965).

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