Hydrogels capable of supporting cell growth

Details Hydrogels capable of supporting cell growth Hydrogels capable of supporting cell growth

1983-12-07

1986-01-21

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435948, C12N 500, C12R 191

Patent

active

045657840

ABSTRACT:
A method of growing anchorage-dependent cells is disclosed in which a substrate comprising a hydrogel is employed. The hydrogel is formed from an aqueous solution gelled with a crosslinked polymer of a hydrophilic monomer and includes a macromolecule capable of supporting cell growth.

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patent: 4268131 (1981-05-01), Miyata et al.
Kleinman et al., "Preparation of Collagen Substrates for Cell Attachment; Effect of Collagen Concentration and Phosphate Buffer", Analytical Biochemistry 94 pp. 308-312 (1979).
Carbonetto et al., "Nerve Fiber Growth on Defined Hydrogel Substrates", Science 216 pp. 897-899 (1982).
Civerchia-Perez, "Use of Collagen-Hydroxyethylmethacrylate Hydrogels for Cell Growth", Proceedings of the National Academy of Sciences 77(4) pp. 2064-2068 (1980).
Faris et al., "Effect of Protein-Hydroxyethylmethacrylate Hydrogels on Cultured Endothelial Cells", Experimental Cell Research 143 pp. 15-25 (1983).

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