Hydrogel particle formulation

Details Hydrogel particle formulation Hydrogel particle formulation

2006-04-04

2006-04-04

Kishore, Gollamudi S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Chewing gum type

C424S499000, C424S500000, C424S501000

Reexamination Certificate

active

07022313

ABSTRACT:
New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.

REFERENCES:
patent: 4853226 (1989-08-01), Michida et al.
patent: 4925677 (1990-05-01), Feijen
patent: 4945050 (1990-07-01), Sanford et al.
patent: 4978069 (1990-12-01), Anderson et al.
patent: 4994276 (1991-02-01), Baichwal et al.
patent: 5036006 (1991-07-01), Sanford et al.
patent: 5041292 (1991-08-01), Feijen
patent: 5053332 (1991-10-01), Cook et al.
patent: 5630796 (1997-05-01), Bellhouse et al.
patent: 5700459 (1997-12-01), Krone et al.
patent: 5952232 (1999-09-01), Rothman
patent: 0 357 401 (1990-03-01), None
patent: 0357401 (1990-07-01), None
patent: 2245831 (1992-01-01), None
patent: 2 245 831 (1992-01-01), None
patent: WO 91/07487 (1991-05-01), None
patent: WO 94/09819 (1994-05-01), None
patent: WO 94/24263 (1994-10-01), None
patent: WO 95/13798 (1995-05-01), None
patent: WO 98/13798 (1995-05-01), None
patent: WO 96/04947 (1996-02-01), None
patent: WO 96/12513 (1996-05-01), None
patent: WO 96/20022 (1996-07-01), None
patent: WO 96/25190 (1996-08-01), None
patent: WO 97/34652 (1997-09-01), None
patent: WO 97/48485 (1997-12-01), None
patent: WO 98/10750 (1998-03-01), None
patent: WO 99/01168 (1999-01-01), None
patent: WO 99/01169 (1999-01-01), None
patent: WO 00/13573 (2000-03-01), None
patent: WO 00/14547 (2000-03-01), None
patent: WO 00/15263 (2000-03-01), None
patent: WO 00/19982 (2000-04-01), None
patent: WO 00/43058 (2000-07-01), None
Aasted, Bent, “Highly purified Agarose as Stacking Gel in Sodium Dodecyl Sulphate/Polyacrylamide-Gel Electrophoresis,”Biochem. J. 189:183-184 (1980).
Albright et al., “Diet, Apoptosis, and Carcinogenesis,”Adv. Exper. Med. And Biol. 422:92-107 (1997).
Cadic-Amadeuf et al., “Inflammatory Reaction Induced by Agarose Implants Reduced by Adding Adrenal Cells to the Polymer,”ASAIO Journal 38(3);M386-M389 (1992).
Anderson and Hagel, “Some Properties and Applications of Superose 6B,”Analytical Biochemistry 141:461-465 (1984).
Andrasko, Jan, “Water in Agarose Gels Studies by Nuclear Magnetic Resonance Relaxation in the Rotating Frame,”Biophys. Journal 15(12):1235-1243 (1975).
Arndt, E.R. and Stevens, E. S., “Anhydro Sugar and Linkage Contributions to Circular Dichroism of Agarose and Carrageenan, With Conformational Implications,” 303:73-78 (1997).
Arnott et al., “The Agarose Double Helix and Its Function in Agarose Gel Structure,”J. Mol. Biol. 90:269-284 (1975).
Arshady, Reza, “Microspheres for Biomedical Applications: Preparation of Reactive and Labelled Microspheres,”Biomaterials 14(1):5-15 (1993).
Artursson et al., “Biodegradable Microspheres, 1. Duration of Action of Dextranase Entrapped in Polyacrylstarch Microparticles in Vivo,”The Journal of Pharmacology and Experimental Therapeutics 231(3):705-712 (1986).
Ayimg id="CUSTOM-CHARACTER-00001" he="2.12mm" wi="1.78mm" file="US07022313-20060404-P00701.TIF" alt="custom character" img-content="character" img-format="tif" ?img id="CUSTOM-CHARACTER-00002" he="2.12mm" wi="1.78mm" file="US07022313-20060404-P00702.TIF" alt="custom character" img-content="character" img-format="tif" ?k et al., “Method of Obtaining Agarose from Agar-Agur,”Lab Delo 6:370-371 (1976).
Bourrillos, et al., “An Improved Method for Preparing Agarose,”Biochim. Biophys. Acta 111:334-336 (1965).
Brogren, Carl-Henrik, “Brownian Motion and Electrophorectic Transport in Agarose Gels Studies by Epilfluorescence Microscopy and Single Particle Tracking Analysis,”J. Phys. Chem. B. 101:5659-5663 (1997).
Bulone et al., “Mesoscopic Gels at Low Agarose Concentrations: Perturbation Effects of Ethanol,”Biophysical Journal 72:388-395 (1997).
Muro-Cacho, Carlos A., “In Situ PCR: Overview of Procedures and Applications,”Frontiers in Bioscience 2:15-19 (1997).
Chan et al., “An Inexpensive Solid Medium for Obtaining Colony-Forming Units of Oral Spirochetes,”Oral Microbiology Immunology 12:372-376 (1997).
Coppi et al., “Polysaccharide Film-Coating Process for Freely Swellable Hydrogels,”Pharmaceutical Development and Technology 3(3):347-353 (1998).
Cowan, D. E., “Thermophilic Proteins: stability and Function in Aqueous and Organic Solvents,”Comp. Biochem. Physiol. 118A(3):429-438 (1997).
Davies et al., “Improved Manufacture and Application of an Agarose Magnetizable Solid-Phase Support,”Appl. Biochem. Biotechnol. 68(1-2):95-112 (1997).
Davis, S.S. and Illum, L., “Polymeric Microspheres as Drug Carriers,”Biomaterials 9(1):111-115 (1988).
Draye et al., “In vitro Characteristics of bioactive Molecules from Dextran Dialdehyde Cross-Linked Gelatin Hydrogel Films,”Biomaterials 19:99-107 (1998).
Eppstein et al., “Alternative Delivery Systems for Peptides and Proteins As Drugs,”CRC Critical Reviews in Therapeutic Drug Carrier System 5(2):99-139 (1998).
Gehrke et al., “Enhanced Loading and Activity Retention of Bioactive Proteins in Hydrogel Delivery Systems,”Journal of Controlled Release 55:21-33 (1998).
Gombotz, W. and Pettit, DK., “Biodegradable Polymers for Protein and Peptide Drug Delivery,”Bioconjugate Chem. 6(4):332-351 (1995).
Gribnau et al., “Microscopic Observations on Commercial Sepharose Deviations From Normal Bead-Structure,”FEBS Letters 57(3):301-303 (1975).
Gustavsson et al., “Superporous Agarose Beads as a Hydrophobic Interaction Chromatography Support,”Journal of Chromatography A 830:275-284 (1999).
Gustavsson et al., Continuous Superporous Agarose Beds for Chromatography and Electrophoresis,Journal of Chromatography A 832:29-39 (1999).
Häglund et al., “Dissolution Controlled Drug Release From Agarose Beads,”Drug Development and Industrial Phamacy 20(6):947-959 (1994).
Hjertén, S. and Liao, J., “High-Performance Liquid Chromatography of Proteins on Compressed, Non-Porous Agarose Beads,”Journal of Chromatography 457:165-174 (1988).
Holloway et al., “Agarose-Encapsulated Adsorbents,”The International Journal of Artificial Organs 2(1):81-86 (1979).
Howe, F.A., “Relaxation times in Paramagnetically Doped Agarose Gels as a Function of Temperature and Ion Concentration,”Magnetic Resonance Imaging 6:263-270 (1988).
Ito et al., “Quantitative Prediction of in Vitro Drug Clearance and Drug Interactions from in Vitro data on Metabolism, Together with Binding and Transport,”Annu. Rev. Pharmacol. Toxicol. 38:461-499 (1998).
Frank-Kamenetskii, M., “ A Simple Solution to the Stability of the Double Helix?,”Nature 324:p. 305 (1986).
Kanke et al., “Clearance of141Ce-Labeled Microspheres from Blood and Distribution in Specific Organs Following Intravenous and Intraarterial Administration in Beagle Dogs,”Journal of Pharmaceutical Sciences 69(7):755-762 (1980).
Kim et al., “Hydrogels: Swelling, Drug Loading, and Release,”Pharmaceutical Research 9(3):283-290 (1992).
Kikuchi et al., “Effect of Ca2+-Alginate Gel Dissolution on Release on Dextran with Different Molecular Weights,”Journal of Controlled Release 58:21-28 (1999).
Jani, G.K., and Gohel, M.C., “Effects of Selected formulation Parameters on the Entraptment of Diclofenac Sodium in Ethyl Cellulose Microspheres,”Journal of Controlled Release 43:245-250 (1997).
Kuijpers et al., “Controlled Delivery of Antibacterial Proteins From Biodegradable Matrices,”Journal of Controlled Release 53:235-247 (1998).
Li et al., “High-Performance Liqui

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