Hydrogel-forming polymeric materials

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...

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Details

351160R, 351160H, 526264, C08F22020, C08F22610, C08L 3102, G02C 704

Patent

active

044304587

ABSTRACT:
Polymeric materials suitable for bio-medical applications, particularly in making contact lenses, are formed by copolymerization and crosslinking of: (1) an amide of an unsaturated carboxylic acid such as acrylamide or methacrylamide; (2) an N-vinyl lactam, such as N-vinyl pyrrolidone; (3) an ester of an unsaturated carboxylic acid, such as a hydroxy-substituted ester of acrylic or methacrylic acid; (4) an unsaturated carboxylic acid, such as acrylic or methacrylic acid; and (5) a polymerizable hydrophobic vinyl monomer, such as styrene; crosslinking with a crosslinking agent either being carried out during copolymerization or subsequently. The resulting polymeric materials may be machined to produce a contact lens form and then hydrated to form a hydrogel which is suitable for use as an extended wear contact lens.

REFERENCES:
patent: 3767731 (1973-10-01), Seiderman
patent: 3839304 (1974-10-01), Hovey
patent: 3937680 (1976-02-01), de Carle
patent: 4036788 (1977-07-01), Steckler
patent: 4042552 (1977-08-01), Grucza
patent: 4123407 (1978-10-01), Gordon
patent: 4123408 (1978-10-01), Gordon

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