Hydroformylation process

Catalyst – solid sorbent – or support therefor: product or process – Catalyst or precursor therefor – Organic compound containing

Reexamination Certificate

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C502S213000, C568S454000, C568S852000, C568S862000

Reexamination Certificate

active

11888919

ABSTRACT:
A process for the production of 4-hydroxybutyraldehyde is described. The process comprises reacting allyl alcohol with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst system comprising a rhodium complex and a trans-1,2-bis(bis(3,5-di-n-alkylphenyl)phosphinomethyl)-cyclobutane. The process gives high yield of 4-hydroxybutyraldehyde compared to 3-hydroxy-2-methylpropionaldehyde.

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Townsend et al. Crystal Structure of (Hexadeuteriobenzene)[(1R,2R)-trans-1,2-bis( (di-phenylphosphino)methyl) cyclobutane] rhodium (I) Perchlorate : A Model for the Resting State of an Asymmetric Hydrogenation Catalyst. Inorganic Chemistry, 1981, vol. 20, pp. 269-271.

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