Hydrocephalus treatment

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing

Reexamination Certificate

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C435S069100, C435S069400, C530S399000

Reexamination Certificate

active

07618614

ABSTRACT:
A method and compound for treatment of hydrocephalus is presented. Hepatocyte growth factor (HGF) is administered intraventricularly.

REFERENCES:
patent: 5840311 (1998-11-01), Nakamura et al.
patent: 2002/0013265 (2002-01-01), Schwartz
patent: A 7-300426 (1995-11-01), None
Tsuzuki et al., Neurological Research, 23(4): 417-424, Jun. 2001.
Tsuzuki et al. Acta Neurochirurgica Supplement, 76:311-316, 2000.
Fukumizu et al., Pediatric Neurology, 13(3):230-234, published Oct. 1995.
Y. Tsuboi et al., “Hepatocyte Growth Factor in Cerebrospinal Fluid in Neurologic Disease”, ACTA Neurologica Scandinavica, vol. 106, pp. 99-103, 2002.
Tsuyoshi Tada et al., “Intraventricular Administration of Hepatocyte Growth Factor Treats Mouse Communicating Hydrocephalus Induced by Transforming Growth Fact β1”, Neurobiology of Disease, vol. 21, pp. 576-586, 2006.
Di Rocco et al., “Anatomo-Clinical Correlations in Normotensive Hydrocephalus,” Journal of the Neurological Sciences, vol. 33, pp. 437-452, 1977.
Yasargil et al., “Hydrocephalus following spontaneous subarachnoid hemorrhage, Clinical features and treatment,” J. Neurosurg., vol. 39, pp. 474-479, Oct. 1973.
Almuneef et al., “Childhood Bacterial Meningitis in Saudi Arabia,” Journal of Infection, vol. 36, pp. 157-160, 1998.
Daoud et al., “Indications and Benefits of Computed Tomography in Childhood Bacterial Meningitis,” Journal of Tropical Pediatrics, vol. 44, pp. 167-169, Jun. 1998.
Gomes et al., “Prognosis of Bacterial Meningitis in Children,” Arq Neuropsiquiatr, vol. 54, No. 3, pp. 407-411, 1996.
Grimwood et al., “Adverse Outcomes of Bacterial Meningitis in School-Age Survivors,” Pediatrics, vol. 95, No. 5, pp. 646-656, May 1995.
Youmans, J.R., Chapter 36; “Hydrocephalus in Childhood,” Neurological Surgery, Fourth Edition, vol. 2, W.B. Saunders Company, Philadelphia, pp. 890-926, 1996.
Graff-Radford et al., “Factors Associated With Hydrocephalus After Subarachnoid Hemorrhage, A Report of the Cooperative Aneurysm Study,” Arch Neurol, vol. 46, pp. 744-752, Jul. 1989.
Pfister et al., “Spectrum of Complications During Bacterial Meningitis in Adults, Results of a Prospective Clinical Study,” Arch. Neurol, vol. 50, No. 6, pp. 575-581, Jun. 1993.
Lobato et al., Hydrocephalus in cerebral cysticercosis, Pathogenic and therapeutic considerations, J. Neurosurg., vol. 55, pp. 786-793, Nov. 1981.
Torvik et al., “Transitory Block of the Arachnoid Granulations Following Subarachnoid Haemorrhage: A Postmortem Study,” Acta Neurochirurgica,vol. 41, pp. 137-146, 1978.
Akai et al., “Normal Pressure Hydrocephalus, Neuropathological Study,” Acta Pathol. Jpn., vol. 37, No. 1, pp. 97-110, 1987.
Massicotte et al., “Human arachnoid villi response to subarachnoid hemorrhage: possible relationship to chronic hydrocephalus,” J. Neurosurg., vol. 91, pp. 80-84, Jul. 1999.
Motohashi et al., Subarachnoid Haemorrhage Induced Proliferation of Leptomeningeal Cells and Deposition of Extracellular Matrices in the Arachnoid Granulations and Subarachnoid Space, Acta Neurochir, vol. 136, pp. 88-91, 1995.
Kang et al., “Long-term follow-up of shunting therapy,” Child's Nerv Syst, vol. 15, pp. 711-717, 1999.
Sgouros et al., “Long-Term Complications of Hydrocephalus,” Pediatr Neurosurg, vol. 23, pp. 127-132, 1995.
Del Bigio, “Epidemiology and Direct Economic Impact of Hydrocephalus: A Community Based Study,” Can J. Neurol. Sci., vol. 25, pp. 123-126, 1998.
Nakamura et al., “Molecular cloning and expression of human hepatocyte growth factor,” Nature, vol. 342, pp. 440-443, Nov. 23, 1989.
Miyazawa et al., “Molecular Cloning and Sequence Analysis of the cDNA for a Human Serine Protease Responsible for Activation of Hepatocyte Growth Factor,” The Journal of Biological Chemistry, vol. 268, No. 14, pp. 10024-10028, 1993.
Dohi et al., “Hepatocyte Growth Factor Attenuates Collagen Accumulation in a Murine Model of Pulmonary Fibrosis,” Am J Respir Crit Care Med, vol. 162, pp. 2302-2307, 2000.
Matsuda et al., “Hepatocyte Growth Factor Suppresses the Onset of Liver Cirrhosis and Abrogates Lethal Hepatic Dysfunction in Rats,” J. Biochem, vol. 118, No. 3, pp. 643-649, 1995.
Fujimoto, “Hepatology: Microcirculation and Pathogenesis of Alcoholic Liver Injury, Gene therapy for liver cirrhosis,” Journal of Gastroenterology and Hepatology, vol. 15 (Suppl.), pp. D33-D36, 2000.
Vargas et al., “Hepatocyte growth factor in renal failure: Promise and reality,” Kidney International, vol. 57, pp. 1426-1436, 2000.
Rosen et al., “Scatter Factor and thec-MetReceptor: A Paradigm for Mesenchymal/Epithelial Interaction,” The Journal of Cell Biology, vol. 127, No. 6, Part 2, pp. 1783-1787, Dec. 1994.
Brinkmann et al., “Hepatocyte Growth Factor/Scatter Factor Induces a Variety of Tissue-Specific Morphogenic Programs In Epithelial Cells,” The Journal of Cell Biology, vol. 131, No. 6, Part 1, pp. 1573-1586, Dec. 1995.
Ohmichi et al., “Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development,” Development, vol. 125, pp. 1315-1324, 1998.
Matsumoto et al., “Hepatocyte growth factor in renal regeneration, renal disease and potential therapeutics,” Current Opinion in Nephrololgy and Hypertension, vol. 9, pp. 395-402, 2000.
Flood et al., “Transforming Growth Factor-β1 in the Cerebrospinal Fluid of Patients with Subarachnoid Hemorrhage: Titers Derived From Exogenous and Endogenous Sources,” Journal of Cerebral Blood Flow and Metabolism, vol. 21, pp. 157-162, 2001.
Takizawa et al., “Inflammatory cytokine cascade released by leukocytes in cerebrospinal fluid after subarachnoid hemorrhage,” Neurological Research, vol. 23, pp. 724-730, Oct. 2001.
Ossege et al., “Expression of tumor necrosis factor-α and transforming growth factor-β1 in cerebrospinal fluid cells in meningitis,” Journal of the Neurological Sciences, vol. 144, pp. 1-13, 1996.
Hunag et al., “Level of transforming growth factor beta 1 is elevated in cerebrospinal fluid of children with acute bacterial meningitis,” J. Neurol, vol. 244, pp. 634-638, 1997.
Galbreath et al., “Overexpression of TGF-β1 in the Central Nervous System of Transgenic Mice Results in Hydrocephalus,” Journal of Neuropathology and Experimental Neurology, vol. 54, No. 3, pp. 339-349, May 1995.
Wyss-Coray et al., “Increased Central Nervous System Production of Extracellular Matrix Components and Development of Hydrocephalus in Transgenic Mice Overexpressing Transforming Growth Factor-β1,” American Journal of Pathology, vol. 147, No. 1, pp. 53-67, Jul. 1995.
Cohen et al., “Characterization of a model of hydrocephalus in transgenic mice,” J. Neurosurg., vol. 91, pp. 978-988, Dec. 1999.
Stoddart, Jr. et al., “Transgenic Mice with a Mutated Collagen Promoter Display Normal Response During Bleomycin-Induced Fibrosis and Possess Neurological Abnormalities,” Journal of Cellular Biochemistry, vol. 77, pp. 135-148, 2000.
Hayashi et al., “Chronological Changes of Cerebral Ventricular Size in a Transgenic Model of Hydrocephalus,” Pediatric Neurosurgery, vol. 33, No. 4, pp. 182-187, 2000.
Morris, “Spatial Localization Does Not Require the Presence of Local Cues,” Learning and Motivation, vol. 12, pp. 239-260, 1981.
Sarnyai et al., “Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin1Areceptors,” PNAS, vol. 97, No. 26, pp. 14731-14736, Dec. 19, 2000.
Cruz et al., “Observations on the use of medetomidine/ketamine and its reversal with atipamezole for chemical restraint in the mouse,” Laboratory Animals, vol. 32, No. 1, pp. 18-22, Jun. 9

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