Hydrocarbon substituted pyrrolidinones, intermediates therefor,

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548542, C07D207273, A61K 3140

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active

049258672

ABSTRACT:
Compounds of formula (I) and pharmaceutically acceptable acid addition salts thereof: ##STR1## wherein R represents a hydrocarbon group, X represents oxygen or sulphur, and R and --NH.sub.2 are cis; are of use in the treatment and/or prevention of neurodegenerative disorders, and are also useful as anticonvulsant agents and muscle relaxants.

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patent: 4863953 (1989-09-01), Leeson et al.
Coll. Czech. Chem. Co. . . . , 1959, 24, 1672.
Evans et al., Brain Research, 1978, 148, 536-542.

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