Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent
Patent
1995-12-14
1998-03-31
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Ultrasound contrast agent
424 95, 424455, 514937, 514749, A61K 4904, A61K 3103
Patent
active
057335265
ABSTRACT:
Novel hydrocarbon oil/fluorochemical preparations and methods for their use are provided. The preparations, which preferably comprise a fluorophilic dispersing agent, may be in the form of hydrocarbon oil-in-fluorochemical dispersions or in the form of a multiple emulsion comprising a polar liquid continuous phase and are particularly useful for administering bioactive agents. In particular the preparations of the present invention may be used to control the bioavailability and improve the efficacy of lipophilic bioactive agents having limited solubility in an aqueous physiological environment.
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Dellamary Luis A.
Krafft Marie-Pierre
Riess Jean G.
Tarara Thomas E.
Trevino Leo A.
Alliance Pharmaceutical Corp.
Hartley Michael G.
Hollinden Gary E.
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