Hydrazono derivatives of cephalosporins

Details Hydrazono derivatives of cephalosporins Hydrazono derivatives of cephalosporins

1978-06-07

1979-12-11

Wheeler, David

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 22, 544 24, 544 25, 544 26, 544 27, 544 28, 2603473, 560 34, 549 77, C07D50136, C07D50132

Patent

active

041784448

ABSTRACT:
Hydrazono derivatives of cephalosporins of the formula ##STR1## wherein R is phenyl optionally substituted, 2- or 3-thienyl optionally substituted, or 2- or 3-furyl optionally substituted, R.sub.1 is hydrogen or alkyl having from 1 to 4 carbon atoms, and R.sub.2 is hydrogen, acetoxy, carbamoyloxy or a heterocyclic nucleus preferably bounded through a sulphur atom to the methylene group. The compounds have bactericidal activity. Methods of preparation are also disclosed.

REFERENCES:
patent: 3971778 (1976-07-01), Cook et al.
patent: 3998950 (1976-12-01), Broggi et al.
Morrison et al. "Organic Chemistry", p. 633, (1966).

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