Hydrazones

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564225, 564226, 564227, C07C28100

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active

056399111

ABSTRACT:
Compounds of formula I ##STR1## wherein A, X, Z and R.sub.1 -R.sub.5 are as defined in the description, and their salts have valuable pharmaceutical properties and are effective especially against tumours. They are prepared in a manner known per se.

REFERENCES:
patent: 3558654 (1971-01-01), Bamford et al.
patent: 3956363 (1976-05-01), Shen et al.
patent: 4076726 (1978-02-01), Pannemann et al.
patent: 4080449 (1978-03-01), Croisier et al.
patent: 4971986 (1990-11-01), Stanek et al.
Chem Abst 104:207159v (1986), Stegelmeier, Hartmut et al, Amidinohydrazones of Tetralin, Chromone, thio chromone, and tetrahydroquinnline and their use in pharmaceuticals.
Juhani Janne et al, Biochem J. (1984) 218, 947-951 "Inhibition of S-adenosylmethionine decarboxylase and diamine oxidase activities by analogues of methylglyoxal bis (guanylhydrazone) and their cellular uptake during lymphocyte activation".
Patai (ed); "The Chemistry of Amidines and imidaks". Wiley and Sons, London 1975 pp. 303-304.
Williams-Ashman et al; Biochem, Brophys Res. Commun 46,288 (1972) "Methyl Glyoxal Bis (guanylhydrazone) as a Potent S-adenosylmethionine Decorboxyleses".
Dondoni, J. Chem. Soc. Chem Commun 1975, 761-762, "Synthetic Reactions using Transition Metal Complexes. Conversion of Amide Oximes into Amidines by Pentacarbonylicon and Evidence for Imine Intermediates in the Deoximation of Ketoximes".
Adamczyk et al, J. Org. Chem. 1984, 49 4226-4237, "Synthesis of Biological Markers in Fossil Fuels. 2. Synthesis and 3. CNMR Studies of Substituted Indans and Tetralins".
Chem. Abstract 109:92791d (1988) Bayer; A. et al Preparation of N-amidino-N'-benzopyranyl and thiopyranylhydrazones as cardiovascular agents.
Chem Abstract (1958) 14678a, Farbwerke Hoechst Basic Phenylhydrazones.
Chem Abstract 105:6283c (1986). Gan et al. "Synthesis of Indanones and Tetralones as new potential Schistosom icidals" Yaoxue Xuebao 1985, 20(5) 342-52.
Misra et al, J. Indian Chem Soc, vol. 52, Oct. 1975, 981-82. "Synthesis and Antibacterial Activity of Thiosemicarbazoues and Hydrazones Derived from Indanone-1."
Chem. Abstract 107:77634v (1987) Anthelmintic pyridinyl acylhydrazones, Rector, Douglas et al.
Sam et al. J. Pharmacol. Sci 53, 1364-1368 (1965) "Potential Antineoplastic Agents Derived From 1,2-Epoxgindan."
Chatterjea et al, J. Indian Chem Soc. 37, No. 8, 1960 pp. 443-450. "The course of Cyclization of X-Benzylhomophthalic Acids."
Miyake et al; Chem Pharm Bull, 31, (7) 2329-2348 (1983) "Synthesis of 2-(N-Substituted amine)-6-hydroxy-1,2,3,4-tetrahydronaphthalen-1-01 Derivatives".
Munavalli et al, Bull. Soc. Chem. France 1964(12) pp. 3103-3112. "Synthese de derives indaniques", & corresponding Chem Abstract 62:7702e-7703h. Synthesis of Indian Derivatives Munavalli, Somashekhar et al.
Jackson et al, J. Chem. Soc. Perkin Trans. 1974, pp. 1911-1920, "Phenol Oxidation Part III, Synthesis of the Benzylisoquinoline Alkaloid Cularine".
Bartmann et al, J. Heterocyclic Chem. 24, 677-682, 1987, "Synthesis of Di-and Tetra alkyl-3-piperazinoisoquinolines and Related Compounds as Potential Antidepressant Agents".
Sakar et al, Indian J. Chem., vol. 24B, Oct. 1985, pp. 1061-1064, "One Step Preparation of Same Synthetically Useful Indanones".
Klein et al, J. Org. Chem., vol. 22, 1019-1021, Sep. 1957 "Synthesis of 8-Bromo-1-methyloaphthalene from o-Bromoacetophenone".

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