Hydrazino and hydroxyamino-14-.beta.-hydroxyandrostane derivativ

Details Hydrazino and hydroxyamino-14-.beta.-hydroxyandrostane derivativ Hydrazino and hydroxyamino-14-.beta.-hydroxyandrostane derivativ

1995-05-18

1997-02-04

Prior, Kimberly J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514176, 514182, 540106, 540108, 540109, 540112, 540113, 552522, 552540, 552548, 552554, 552563, 552582, 552610, A61K 3158

Patent

active

055998062

ABSTRACT:
The invention describes hydrazino and hydroxyamino-14.beta.-hydroxyandrostane derivatives having general formula (I): ##STR1## wherein the symbol means .alpha. or .beta. configuration and A, B, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 have the meanings given in the description and their use in the treatment of cardiovascular disorders such as heart failure and hypertension.

REFERENCES:
patent: 5324719 (1994-06-01), Frigerio et al.
patent: 5444055 (1995-08-01), Cerri et al.

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