Hydrazide compounds with angiogenic activity

Details Hydrazide compounds with angiogenic activity Hydrazide compounds with angiogenic activity

2008-05-06

2008-05-06

Buttner, David (Department: 1796)

Stock material or miscellaneous articles

Composite

Of polycarbonate

C428S474400, C428S480000, C525S408000, C525S409000, C525S430000, C525S437000, C525S439000, C525S447000, C525S449000, C525S467000, C525S534000, C525S540000

Reexamination Certificate

active

07368169

ABSTRACT:
Compounds exhibiting angiogenic properties incorporating the structure of Formula I:in-line-formulae description="In-line Formulae" end="lead"?R3—NH—NH—C(═O)—R2—P—R1  (I)in-line-formulae description="In-line Formulae" end="tail"?wherein P is a water-soluble, biodegradable polymer, R1is hydrogen, lower alkyl, lower alkoxy or —R2—C(═O)—NH—NH—R3; each R2is independently —CH2—, —NH— or O; and each R3is independently hydrogen or a residue of a naturally occurring alpha-L-amino acid or dipeptide thereof. Polymer networks crosslinked with hydrazide compounds are also disclosed, together with implantable medical devices incorporating the compounds and crosslinked polymers, and angiogenesis-promoting treatment methods, including wound-treatment methods.

REFERENCES:
patent: 5099060 (1992-03-01), Kohn et al.
patent: 5198507 (1993-03-01), Kohn et al.
patent: 5216115 (1993-06-01), Kohn et al.
patent: 5587507 (1996-12-01), Kohn et al.
patent: 5658995 (1997-08-01), Kohn et al.
patent: 5670602 (1997-09-01), Kohn et al.
patent: 6048521 (2000-04-01), Kohn et al.
patent: 6103255 (2000-08-01), Levene et al.
patent: 6261585 (2001-07-01), Sefton et al.
patent: 6284862 (2001-09-01), Kohn et al.
patent: 6319492 (2001-11-01), Kohn et al.
patent: 2002/0049281 (2002-04-01), Zhao et al.
patent: 2001064385 (2001-03-01), None
Vercruysse; “Synthesis and in Vitro Degradation of New Polyvalent Hydrazide Crosslinked Hydrogels of Hyaluronic Acid” Bioconjugate Chemistry, 1997 vol. 8 pp. 686-694.
Derwent Abstract of IL 605869 Apr. 30, 1984.
Pine; Organic Chemistry 4thedition 1980, pp. 785-787.

Affiliated with

Also associated with

Rating

Hydrazide compounds with angiogenic activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hydrazide compounds with angiogenic activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydrazide compounds with angiogenic activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2806031