Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-05-10
2005-05-10
Raymond, Richard (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S311000, C514S385000, C514S396000, C514S399000, C514S409000, C514S412000, C514S422000, C514S425000, C548S300100, C548S300700, C548S407000, C548S408000, C548S409000, C546S112000, C546S134000, C546S016000
Reexamination Certificate
active
06890915
ABSTRACT:
The present application describes novel hydantoin derivatives of formula (I):or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, R1, R2, R3, R4, R5, R6, R7, R11, and n are defined in the present specification, which are useful as inhibitors of matrix metalloproteinases (MMP), TNF-α converting enzyme (TACE), aggrecanase, or a combination thereof.
REFERENCES:
patent: 151744 (1973-11-01), None
patent: 5213957 (1993-08-01), None
patent: 123363 (2001-04-01), None
patent: WO 02074748 (2002-09-01), None
patent: WO 02074749 (2002-09-01), None
patent: WO 02074750 (2002-09-01), None
patent: WO 02074751 (2002-09-01), None
patent: WO 02074752 (2002-09-01), None
patent: WO 02074767 (2002-09-01), None
PubMeed Abstract 145790524, also cited as Curr. Opin. Drug Disc.,6/5,742-59(2003).*
PubMed Abstract 11934805, also cited as Br J. Pharmacol. 135/7, 1655-64(2002).*
PubMed Abstract 12082286, also cited as Biorheology, 39/1-2, 237-46(2002).*
PubMed Abstract 14524529, also cited as Clin.Exp.Metastasis, 20/5,407-12(2003).*
Chemical Abstract DN 120:271177, also cited as Sawanishi et al.,JP 5213957.*
Aharony et al, Pharmacological Characterization of a New Class of Non-Peptide Neurokinin A Antagonists that Demonstrate Species Selectivity, J. Pharmacol. Exp. Ther. (1995) 274 (3) 1216-21.
Duan Jingwu
Sheppeck James E.
Wasserman Zelda
Xue Chu-Biao
Belfzeld Jing S.
Bristol-Myers Squibb Pharma Company
Patel Sudhaker B.
Raymond Richard
LandOfFree
Hydantoins and related heterocycles as inhibitors of matrix... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hydantoins and related heterocycles as inhibitors of matrix..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydantoins and related heterocycles as inhibitors of matrix... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3418252