Hydantoin derivatives as inhibitors of matrix...

Details Hydantoin derivatives as inhibitors of matrix... Hydantoin derivatives as inhibitors of matrix...

2006-09-05

2006-09-05

Tsang, Cecilia (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S115000, C562S490000, C514S187000, C514S481000

Reexamination Certificate

active

07102008

ABSTRACT:
The present invention provides compounds of Formula (I):or a stereoisomer or pharmaceutically acceptable salt form thereof, wherein the variables A, R1, R2, R3, R4, Z, U, X, Y, Za, and n are defined are as defined herein, which are useful as inhibitors of matrix metalloproteinases (MMP) and/or TNF-α converting enzyme (TACE), or a combination thereof.

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