Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1975-07-28
1978-08-08
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548312, H61K 31415, C07D23320
Patent
active
041057740
ABSTRACT:
Hydantoin derivatives of varying lipophilic character were prepared as nigen mustard carriers for CNS anti-tumor evaluation in transplanted mouse tumor test systems. Activity was studied in the murine ependymoblastoma brain tumor system. Multiple cures were observed for three of the four analogs examined. The compounds were also active in the intraperitoneal leukemia L1210 and P388 systems as well as in B16 melanoma and Lewis lung carcinoma.
REFERENCES:
chemical Abstracts 83:157713w (1975).
Driscoll John S.
Marquez Victor E.
Peng Geoffrey
Goldberg Jerome D.
The United States of America as represented by the Secretary of
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