Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...
Patent
1995-05-17
1997-05-06
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Animal cell, per se, expressing immunoglobulin, antibody, or...
435 7021, 4351721, 435 696, 43525233, 435332, 435336, 5303879, 53038823, 5303873, 5303913, 4241391, 4241451, C12N 518, C12N 522
Patent
active
056270739
ABSTRACT:
Isolated CHF (also referred to cardiac hypertrophy factor or cardiotrophin-1), isolated DNA encoding CHF, hybridomas and cell lines producing antibodies to CHF, and recombinant or synthetic methods of preparing CHF are disclosed. These CHF molecules are shown to influence hypertrophic activity and neurological activity. Accordingly, these compounds or their antagonists may be used for treatment of heart failure, arrhythmic disorders, inotropic disorders, and neurological disorders.
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Baker Joffre
Chien Kenneth
King Kathleen
Pennica Diane
Wood William
Genentech Inc.
Hasak Janet E.
Nucker Christine M.
Reeves Julie E.
The Regents of the University of California
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