Hybridoma cells secreting a monoclonal antibody specific for 5-b

Details Hybridoma cells secreting a monoclonal antibody specific for 5-b Hybridoma cells secreting a monoclonal antibody specific for 5-b

1982-08-20

1985-07-16

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 6, 435 7, 4351722, 435948, 436548, 935103, 935110, C12N 500, C12N 1500, C12Q 168, G01N 3354

Patent

active

045297002

ABSTRACT:
Cells synthesizing DNA are detected in a rapid, non-radioactive assay using the monoclonal antibody reagent secreted by the hybridoma produced in accordance with the present invention. The assay is used to study DNA repair in cells that have been exposed to various environmental toxins, chemotherapeutic agents, and the like. The monoclonal antibody secreted by the hybridoma is a valuable reagent for research and diagnosis.

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Gratzner et al.: Exp. Cell Res. 95, (1975), 88-94, "The Use of Antibody Specific for Bromodeoxyuridine for the Immunofluorescent . . . ".
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Gratzner et al., "An Immunofluorescence Method for Monitoring DNA . . . ", Cytometry, vol. 1, No. 6, 1981, pp. 385-389.

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