Hybridoma cell lines and antibodies that bind noggin

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

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5303879, 53038824, 53038885, C07K 1622, C12N 512

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active

058211241

ABSTRACT:
Novel dorsal growth inducing factors, complexes including the factors, and DNA or RNA coding sequences for the factors are described. Hybridoma cell lines and antibodies that bind to the dorsal growth inducing factor noggin, having the amino acid sequence set forth in SEQ ID NO:2, are also described.

REFERENCES:
patent: 4857637 (1989-08-01), Hammonds et al.
patent: 4933294 (1990-06-01), Waterfield et al.
patent: 5030576 (1991-07-01), Dull et al.
patent: 5177197 (1993-01-01), Kanzaki et al.
patent: 5219759 (1993-06-01), Heldin et al.
patent: 5229500 (1993-07-01), Barde et al.
Basler, et al., "Control of Cell Pattern in the Neural Tube: Regulation of Cell Differentiation by dorsalin-1, a Novel TGFSS Family Member," Cell, 73, (May 21, 1993), pp. 687-702.
Chen, et al., "The Proto-Oncognene C-ros Codes for a Transmembrane Tyrosine Protein Kinase Sharing Sequence and Structural Homology . . . ," Oncogene, 6 (1991), pp. 257-264.
Christian, et al., "Xwnt-8, a Xenopus Wnt-1/int-1-related Gene Responsive to Mesoderm-inducing Growth Factors, May Play A Role in Ventral Mesodermal Patterning During Embryogenesis," Development, 111 (1991), pp. 1045-1055.
Lin, et al., "GDNF: A Glial Cell Line-Derived Neurotrophic Factor for Midbrain Dopaminergic Neurons," Science, 260 (May 21, 1993), pp. 1130-1132.
Sokol, et al., "A Mouse Macrophage Factor Induces Head Structures and Organizes a Body Axis in Xenopus," Science 249, (1990), pp. 561-564.
Weiss, Rick, "Promising Protein for Parkinson's," Science, 260 (May 21, 1993), pp. 1072-1073.
Lamb, "Neural Induction by The Secreted Polypeptide Noggin", Science 262: (1993), pp. 713-718.
Smith, "Secreted Noggin Protein Mimics the Spemann Organizer in Dorsalizing Xenopus Mesoderm", Nature 361, (1993) pp. 547-549.
Slack, "Developmental Biology. Noggin the Dorsalizer", Nature 361, (1993), pp. 498-499.
Smith, "Expression Cloning of Noggin, a New Dorsalizing Factor Localized to the Spemann Organizer in Xenopus Embryos", Cell 70, (1992), pp. 829-840.
Smith, et al, "Injected Xwnt-8 RNA Acts Early in Xenopus Embryos to Promote Formation of a Vegetal Dorsalizing Center", Cell 67, (1991), pp. 753-765.
Chalazonitis, et al., "Transforming Growth Factor Beta Has Neurotrophic Actions on Sensory Neurons In Vitro and Is Synergistic With Nerve Growth Factor", Developmental Biology 152, (1992) pp. 121-132.
Nusse, et al. Cell 69, (1992), pp. 1073-1087.
Barinaga, Science 262, (1993), pp. 653-654.
Pomponi, et al., Aging 2, (1990), pp. 125-153.
Bowie, et al., Science 247, (1987), pp. 1306-1310.

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