Hybridoma capable of producing anti-dectin-1 monoclonal...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

Reexamination Certificate

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C530S388700

Reexamination Certificate

active

07915041

ABSTRACT:
A hybridoma capable of producing a monoclonal antibody against dectin-1, and a monoclonal antibody which specifically reacts with dectin-1.

REFERENCES:
patent: 6046158 (2000-04-01), Ariizumi et al.
patent: 02/096945 (2002-12-01), None
Adachi Yoshiyuki, et al., Characterization of beta-glucan recognition site on C-type lectin, dectin 1., Infection and Immunity. Jul. 2004, vol. 72 No. 7, pp. 4159 to 4171.
Brown, Gordon D. et al., Dectin-1 is a major beta-glucan receptor on macrophages., The Journal of Experimental Medicine. 2002, vol. 196 No. 3, pp. 407 to 412.
Edited by Yukio Sugino, “Bio Technology Seriese Monoclonal Kotai”, Kodansha Ltd., Mar. 10, 1986, pp. 10-11.
Supplementary European Search Report dated Jun. 18, 2008.
Gordon D. Brown, et al., A new receptor for B-glucans, Nature, vol. 413, 36-37 (2001).
Phillip R. Taylor, et al., The B-Glucan Receptor, Dectin-1, Is Predominantly Expressed on the Surface of Cells of the Monocyte/Macrophage and Neutrophil Lineages, Journal of Immunology, vol. 169, pp. 3876-3882 (2002).
Kiyoshi Ariizumi, et al., Identification of a Novel, Dendritic Cell-associated Molecule, Dectin-1, by Subtractive cDNA Cloning, The Journal of Biological Chemistry, vol. 275, pp. 20157-20167 (2000).
International Preliminary Examination Report, May 24, 2007.
Extended European Search Report issued in European Patent Application No. 09158699.0-2402, dated Aug. 11, 2009.
Janet A. Willment, et al.; “The human β-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells”; European Journal of Immunology, Wiley-VCH Verlag GMBH & Co. KGaA; vol. 35, No. 5; May 1, 2005; pp. 1539-1547; XP002412179.

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