Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1989-04-10
1991-04-30
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
435 704, 43524027, C12P 2100, C12N 500
Patent
active
050119125
ABSTRACT:
A particular calcium-dependent monoclonal antibody, 4E11, is produced from a murine hybridoma cell line and is useful for purifying a recombinant fusion protein having an N-terminal identification peptide DYKDDDDK to which the monoclonal antibody binds.
REFERENCES:
Biotechnology Progress, vol. 5, pp. 119-125, W. H. Velander et al., Sep. 1989.
Goodman and Gilman, 4th Edition, 1970, Pharm. Basis of Therapeutics, pp. 948-953.
Biochemistry, 1970, Lehniger, A. L., pp. 149-150, Worth Publishers, New York.
Maurer et al., "Antigenicity of Polypeptides (PolyaAmino Acids): Calcium-Dependent and Independent Antibodies", J. Immunol. 105:567 (1970).
Frankel et al., "Hydrogen Exchange Studies of a Ca.sup.++ Dependent Sheep HSA-Anti HSA System", Fed. Proceed. 36:1286 (1977).
Favre et al., "Influence of Calcium on Angiotensin II-Antibody Reaction", Immunochemistry 10:43 (1973).
Hopp Thomas P.
Prickett Kathryn S.
Cunningham T. M.
Hallquist Scott G.
Immunex Corporation
Moskowitz Margaret
Wight Christopher L.
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