Hybridoma and monoclonal antibody 9H10-A4 specific to an antigen

Details Hybridoma and monoclonal antibody 9H10-A4 specific to an antigen Hybridoma and monoclonal antibody 9H10-A4 specific to an antigen

1994-09-16

1996-11-26

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

5303882, 5303888, 53038885, 5303877, 435 7021, 4351722, C12N 1520, C07K 1618

Patent

active

055784844

ABSTRACT:
Monoclonal antibodies, specifically 9H10-A4 monoclonal antibodies, specific to an epitope present on the surface of LNCaP cells, are produced by hybridoma cell line 9H10-A4 formed by fusing mouse lymphocytes and mouse myeloma cells. 9H10-A4 monoclonal antibodies are useful to positively identify LNCaP cells and distinguish them from other cultured cells, and as a reliable control in competitive binding studies for detection of circulating antigens associated with prostate carcinoma.

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Frankel et al., Proc. Nat'l. Acad. Sci. USA 79:903-907, 1982.
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Finstad et al., Proc. Nat'l. Acad. Sci. USA 82:2955-2959, 1985.
Campbell, "Monoclonal Antibody Technology" Elsevier Publ. 1984.
Wright et al., Cancer Res. 43:5509-5516, 1983.
Horoszewicz et al., Anticancer Res. 7:927-936, 1987.
Horoszewicz et al., 14th International Cancer Congress, Abstracts of Lectures, Symposia, Free Communications vol. 1, 1986 p. 150.
ATCC Catalog of Cell Lines and Hybridomas, 1988, p. 170.

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