Hybrid vector having a cytomegalovirus enhancer and...

Details Hybrid vector having a cytomegalovirus enhancer and... Hybrid vector having a cytomegalovirus enhancer and...

2007-08-28

2007-08-28

Guzo, David (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C435S358000, C435S455000, C435S461000

Reexamination Certificate

active

10465156

ABSTRACT:
An expression vector capable of expressing high levels of heterologous proteins having a cytomegalovirus (CMV) enhancer 5′ upstream from a myeloproliferative sarcoma virus (MPSV) promoter.

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patent: 2003/0103986 (2003-06-01), Rixon et al.
patent: WO00/65074 (2000-11-01), None
Chinnasamy et al., “Lentiviral-medicated gene transfer into human lymphocytes: role of HIV-1 accessory proteins”Blood 96(4):1309-1316, Aug. 2000.
Plavec et al., “High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T cells: implication for gene therapy of AIDS”Gene Therapy 4:128-139, 1997.
Stacey et al., “Comparison ofMyeloproliferative sarcomaVirus with Moloney Murine Sarcoma Virus Variants by Nucleotide Sequencing and Heteroduplex Analysis”Journal of Virology 50(3):725-732, Jun. 1984.
Stocking et al., “Long terminal repeat sequences impart hematopoietic transformation properties to theMyeloproliferative sarcomavirus”Proc. Natl. Acad. Sci. USA 82:5746-5750, Sep. 1985.
Boshart et al., “A Very Strong Enhancer is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus”Cell 41:521-530, Jun. 1985.
Chee, EMBL Database Accession No. X17403, Apr. 2005.
Stacy, EMBL Database Accession No. K01683, Apr. 2005.

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