Hybrid system for solubilizing pharmaceutically active...

Details Hybrid system for solubilizing pharmaceutically active... Hybrid system for solubilizing pharmaceutically active...

2007-08-14

2007-08-14

Smith, Duane (Department: 1724)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

At least one aryl ring which is part of a fused or bridged...

C524S502000, C424S448000, C424S449000, C424S405000, C514S058000, C514S944000, C514S946000, C604S892100, C604S892100, C604S892100, C604S890100

Reexamination Certificate

active

10948763

ABSTRACT:
The present invention is directed to a hybridized polymer matrix, a method of making such, and products incorporating such a matrix. The hybridized polymer matrix comprises a solvent-free polymer matrix base, a hybridized matrix comprising one or more poly(1-vinyl-2-pyrrolidones) and dimethyl sulfoxide, and at least one active substance. The hybridized polymer matrix is useful in the preparation of transdermal therapeutic systems, particularly making possible the introduction of pharmaceutically active substances which are otherwise difficult to dissolve, such as ibuprofen, into a non-polar matrix.

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