Hybrid random bead/chip based microarray

Details Hybrid random bead/chip based microarray Hybrid random bead/chip based microarray

2006-11-30

2010-02-09

Geisel, Kara E (Department: 2877)

Optics: measuring and testing

By shade or color

With color transmitting filter

C356S244000

Reexamination Certificate

active

07659983

ABSTRACT:
A method and apparatus for performing an assay process, featuring providing microbeads in a solution, each microbead having a particle substrate with a grating with a superposition of different predetermined regular periodic variations of the index of refraction disposed in the particle along a grating axis and indicative of a code; placing the microbeads on an alignment substrate; reading codes of the microbeads and the position thereof on the alignment substrate; reading the fluorescence on each microbead and the position order thereof on the alignment substrate; and determining an assay result based on bead position order and bead code of the earlier reading steps.

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