Hybrid proteins with modified activity

Details Hybrid proteins with modified activity Hybrid proteins with modified activity

1999-02-03

2000-04-18

Achutamurthy, Ponnathapura

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

43525233, 435325, 435366, 435 696, 530324, 530350, 530383, 536 235, C12N 120, C12P 2104, A61K 3514, C07H 2104

Patent

active

060514183

ABSTRACT:
Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences encoding the proteins and hosts, including transgenic animals, that possess these DNA sequences; antibodies directed against hybrid proteins; methods of modifying the properties of proteins; and treatment methods employing hybrid proteins.

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