Hybrid proteins with modified activity

Details Hybrid proteins with modified activity Hybrid proteins with modified activity

1997-06-25

1999-02-09

Wax, Robert A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 691, 435 697, 530383, 530324, 530350, 536 235, C12P 2104, C12P 2106, A61K 3514, A61K 3800

Patent

active

058692924

ABSTRACT:
Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences encoding the proteins and hosts, including transgenic animals, that possess these DNA sequences; antibodies directed against hybrid proteins; methods of modifying the properties of proteins; and treatment methods employing hybrid proteins.

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