Hybrid proteins with modified activity

Details Hybrid proteins with modified activity Hybrid proteins with modified activity

1995-11-13

1999-06-08

Jacobson, Dian C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 691, 435 696, 435 697, 514 8, 514834, 530350, 530383, 930100, A61K 3800, A61K 3514, C12P 2104, C12P 2106

Patent

active

059104813

ABSTRACT:
Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences encoding the proteins and hosts, including transgenic animals, that possess these DNA sequences; antibodies directed against hybrid proteins; methods of modifying the properties of proteins; and treatment methods employing hybrid proteins.

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