Hybrid proteins having cross-linking and tissue-binding activiti

Details Hybrid proteins having cross-linking and tissue-binding activiti Hybrid proteins having cross-linking and tissue-binding activiti

1995-11-01

1998-11-03

Walsh, Stephen

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 43525411, 435325, 530350, 530380, 530381, 530382, 536 234, 536 241, 514 12, 514 21, C12P 2104, C07K 1900, C07K 14435, C12N 1562

Patent

active

058307001

ABSTRACT:
Hybrid proteins having cross-linking and tissue-binding activities, DNA molecules encoding such proteins and methods for producing the hybrid proteins from recombinant host cells are disclosed. The hybrid proteins disclosed herein are useful in tissue sealant and wound healing formulations.

REFERENCES:
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4627879 (1986-12-01), Rose et al.
patent: 4661111 (1987-04-01), Ruoslahti et al.
patent: 5136023 (1992-08-01), Hashino et al.
patent: 5428014 (1995-06-01), Labroo et al.
patent: 5514579 (1996-05-01), O'Hara et al.
Sekiguchi et al., Essays in Biochemistry 26: 39-48, 1991.
Prieto et al., J. Cell. Biol. 119: 663-678, 1992.
Lord et al., J. Biol. Chem. 265: 838-843, 1990.
Simon et al. The glutamine residues in transglutaminase-catalyzed cross-linking of involucrin. The Journal of Biological Chemistry. vol. 263, No. 34, pp. 18093-18098, Dec. 5, 1988.
Hohl et al. Charcterization of human loricrin. The Journal of Biological Chemistry. vol. 266, No. 10, pp. 6626-6636, Apr. 5, 1991.
Rixon et al., Biochemistry 22: 3237-3244, 1983.
Chung et al., Biochemistry 22: 3250-3256, 1983.
Doolittle et al., Nature 280: 464-468, 1979.
Pan et al., Proc. Natl. Acad. Sci. USA 89:2066-2070, 1992.
Vibe-Pedersen et al., EMBO J. 3: 2511-2516, 1984.
Obara et al., Cell 53: 649-657, 1988.
Kornblihtt et al., Nuc. Acids Res. 12: 5853-5868, 1984.
Sekiguchi et al., Proc. Natl. Acad. Sci. USA 77: 2661-2665, 1980.
Kornblihtt et al., Proc. Natl. Acad. Sci. USA: 80:3218-3222, 1983.
Hirano et al., Proc. Natl. Acad. Sci. USA 80: 46-50, 1983.
Kornblihtt et al., EMBO J. 4: 1755-1759, 1985.
Pierschbacher et al., J. Biol. Chem. 257: 9593-9597, 1982.
Schwarzbauer et al., Proc. Natl. Acad. Sci. USA 84: 754-758, 1987.
Dufour et al., Exp. Cell. Res. 193: 331-338, 1991.
Yamada, Curr. Opin. Cell. Biol. 1: 956-963, 1989.
Obara et al., FEBS LETT. 213: 261-264, 1987.
Yamada, Ann. Rev. Biochem. 52: 761-799, 1983.
Yabkowitz et al., J. Biol. Chem. 264: 10888-10896, 1989.
Fu et al., Biochemistry 31: 11968-11972, 1992.
Eckert et al., Cell 46: 583-589, 1986.
Robson et al. 1986. Introduction to Protein and Protein Engineering, Elsevier, New York, p. 41.
Pongor, S. 1987. Methods in Enzymology, 154: 450-473.

Affiliated with

Also associated with

Rating

Hybrid proteins having cross-linking and tissue-binding activiti does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hybrid proteins having cross-linking and tissue-binding activiti, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hybrid proteins having cross-linking and tissue-binding activiti will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-688225