Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1986-05-15
1989-05-09
Teskin, Robin
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
435 69, 435 70, 435 91, 4351723, 435320, 43525233, 435849, 935 47, 935 13, 935 29, 935 60, 935 73, 530313, 530324, 530343, 530350, 530380, 530402, 530407, C12P 2100, C12P 2102, A61K 3743, C07K 100, C12N 1500
Patent
active
048289884
ABSTRACT:
A fusion between DNA sequences coding for hAT and hGRF via a synthetic adaptor coding for an in vitro cleavable amino acid sequence is used to express hGRF at high levels in E. coli.
REFERENCES:
patent: 4546082 (1985-10-01), Kurjan et al.
patent: 4617149 (1986-10-01), DiMarchi et al.
patent: 4689318 (1987-08-01), Kaiser et al.
Cravador et al, Biochimie, vol. 67 (7-8), pp. 829-834 Jul. 1985, "Total DNA Synthesis and Cloning in Escherichia coli of a Gene Coding for the Human Growth Hormone Releasing Factor".
Guillemin et al., Science, 218:585 (1982).
Bollen Alex J.
Jacobs Paul
Lentz Edward T.
Lourie Alan D.
Smith Kline - RIT
Teskin Robin
Williams Janice E.
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