Hybrid paucilamellar lipid vesicles

Details Hybrid paucilamellar lipid vesicles Hybrid paucilamellar lipid vesicles

1995-05-31

1997-05-13

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

424450, 4284022, 436829, A61K 9127, B01J 1302

Patent

active

056289367

ABSTRACT:
Disclosed are hybrid paucilamellar lipid vesicles containing a phospho- or glycolipid and a nonionic, anionic, or zwitterionic surfactant in the lipid bilayers. The paucilamellar vesicles may have either an aqueous or oil-filled central cavity. A method of manufacture for these vesicles is also disclosed.

REFERENCES:
patent: 3372261 (1968-03-01), Leary et al.
patent: 3957971 (1976-05-01), Oleniacz
patent: 4133874 (1979-01-01), Miller et al.
patent: 4182330 (1980-01-01), Michaels
patent: 4217344 (1980-08-01), Vanlerberghe et al.
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4241046 (1980-12-01), Papahadjopoulos et al.
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4348329 (1982-09-01), Chapman
patent: 4356167 (1982-10-01), Kelly
patent: 4377567 (1983-03-01), Geho
patent: 4448765 (1984-05-01), Ash et al.
patent: 4485054 (1984-11-01), Mezei et al.
patent: 4536324 (1985-08-01), Fujiwara et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4564599 (1986-01-01), Janoff et al.
patent: 4608211 (1986-08-01), Handjani et al.
patent: 4610868 (1986-09-01), Fountain et al.
patent: 4619913 (1986-10-01), Luck et al.
patent: 4666711 (1987-05-01), Vanlerberghe et al.
patent: 4684625 (1987-08-01), Eppstein et al.
patent: 4692433 (1987-09-01), Hostetler et al.
patent: 4695554 (1987-09-01), O'Connell et al.
patent: 4725442 (1988-02-01), Haynes
patent: 4731210 (1988-03-01), Weder et al.
patent: 4744989 (1988-05-01), Payne et al.
patent: 4772471 (1988-09-01), Vanlerberghe et al.
patent: 4789633 (1988-12-01), Huang et al.
patent: 4855090 (1989-08-01), Wallach
patent: 4911928 (1990-03-01), Wallach
patent: 4917951 (1990-04-01), Wallach
patent: 4942038 (1990-07-01), Wallach
patent: 5147723 (1992-09-01), Wallach
patent: 5234767 (1993-08-01), Wallach
McCutcheon (Detergents & Emulsifiers, 1973, North American Edition), p. 27.
McCutcheon (Emulsifiers & Detergents, 1982, North American Edition), pp. 26-27.
Ostro (Liposomes, 1983, Marcel Dekker, Inc.), pp. 246-249.
Handjani-Vila et al. (Les niosomes, 1985, pp. 297-313).
Bangham et al., Diffusion of Univalent Ions Across the Lamallae of Swollen Phospholipids, J. Mol. Biol. (1965), vol. 13, pp. 238-252.
Gregoriadis, The carrier Potential of Liposomes In Biology and Medicine, New England Journal of Medicine (1976), vol. 295, No. 13, pp. 704-710.
Szoka et al., Procedure for Preparation of Liposomes With Large Internal Aqueous Space and High Capture by Reverse-Phase Evaporation, Proc. Natl. Acad. Sciences USA (1978), vol. 9, pp. 4194-4198.
Dousset et al., Methods de Preparation des Liposomes (1980), pp. 41-72.
Philippot et al., A Very Mild Method Allowing the Encapsulation of Very High Amounts of Macromolecules into Very large (1000mm) Unilamellar Liposomes, Biochimica et Biophysia Acta (1983), vol. 734, pp. 137-143.
Ribier et al., Bilayer Fluidity of Non-ionic Vesicles, An Investigation by Differential Polarized Phase Fluorometry, Colloids and Surfaces (1984), vol. 10, pp. 155-161.
Baillie et al., The Preparation and Properties of Niosomes --Non-ionic Surfactant Vesicles, J. Pharm. Pharmacol. (1985), vol. 37. pp. 863-868.
Phillippot et al., Extemporaneous Preparation of large Unilamellar Liposomes, Biochimica et Biophysia Acta (1985), vol. 821, pp. 79-84.
Puisieux et al., Problems Technologiques Poses par L'utilisation des Liposomes Comme Vecteurs de Substances Medicanenteuses. Encapsulation Sterilisation, Conservation (1985), pp. 73-113.
Baillie et al., Non-ionic Surfactant Vesicles, Niosomes, As a Delivery System for the Anti-Leishmanial Drug, Sodium Stibogluconate, J. Pharm. Pharmacol. (1986), vol. 38, pp. 502-505.

Affiliated with

Also associated with

Rating

Hybrid paucilamellar lipid vesicles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hybrid paucilamellar lipid vesicles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hybrid paucilamellar lipid vesicles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1382656