Hybrid membrane bead and process for encapsulating materials in

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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264 41, 264 43, 264 432, 264 433, 424418, 424455, 424463, 424491, 424493, 435182, 43524022, A61K 916, B01J 1320, B01J 1322, C12N 1104

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054279356

ABSTRACT:
Material such as biological material is encapsulated within a semi-permeable hybrid membrane bead by suspending the material in a medium which comprises an effective amount of a gelling inducer; forming said suspension into a droplet of a size sufficient to envelop said material, suspending a second material in a gelling solution comprising an effective amount of a gel forming polymer which gels upon contact with said gelling inducer forming a discrete bead by contacting the outer surface portion of the droplet with a gelling solution, and allowing the gelling solution to thicken sufficiently for the second material to become entrapped therein.

REFERENCES:
patent: 3522346 (1970-07-01), Chang
patent: 3549555 (1970-12-01), Hiestand et al.
patent: 3725113 (1973-04-01), Chang
patent: 3730841 (1973-05-01), Salvatore et al.
patent: 3860490 (1975-01-01), Guttag
patent: 3954678 (1976-05-01), Marquisee
patent: 3972776 (1976-08-01), Vieth et al.
patent: 4001480 (1977-01-01), Shank
patent: 4076774 (1978-02-01), Short
patent: 4148689 (1979-04-01), Hino et al.
patent: 4251387 (1981-02-01), Lim et al.
patent: 4255411 (1981-03-01), Lim et al.
patent: 4257884 (1981-03-01), Lim
patent: 4322311 (1982-03-01), Lim et al.
patent: 4324683 (1982-04-01), Lim et al.
patent: 4334027 (1982-06-01), Klein et al.
patent: 4352883 (1988-10-01), Lim
patent: 4386895 (1983-06-01), Sodickson
patent: 4389330 (1983-06-01), Tice et al.
patent: 4389419 (1983-06-01), Lim et al.
patent: 4391909 (1983-07-01), Lim
patent: 4407957 (1983-10-01), Lim
patent: 4409331 (1983-10-01), Lim
patent: 4495288 (1985-02-01), Jarvis, Jr. et al.
patent: 4615883 (1986-10-01), Nelson et al.
patent: 4639423 (1987-01-01), Kahlert et al.
patent: 4647536 (1987-03-01), Mosbach et al.
patent: 4744933 (1988-05-01), Rha et al.
patent: 4749620 (1988-05-01), Rha et al.
Nilsson, K. et al., "Entrapment of Animal Cells for Production of Monoclonal Antibodies and Other Biomolecules", Nature, vol. 302, Apr. 14, 1983, pp. 629-630.
Lim et al:, "Microencapsulation of Living Cells and Tissue", J. Pharm. Sci., vol. 70, No. 4, Apr., 1981, pp. 351-354.
Howell, S. L., et al., "Possible Use of Agarose Gels as Encapsulating Media for Transplantation of Islets of Langerhans", Proc. Physiol. Soc., Nov., 1981, pp. 20P-21P.
Gharapetian, H., et al., "Encapsulation of Viable Cells within Polyacrylate Membranes", Biotech. Bioeng., vol. 28, Oct., 1986, pp. 1595-1600.
Chang, T. M. S., "Biodegradable Semipermeable Microcapsules Containing Enzymes, Hormones and other Biologicals", J. Bioeng., vol. 1, 1976, pp. 24-32.
Posillico, E. G., "Microencapsulation Technology for Large-Scale Antibody Production", Biotech., vol. 4, Feb., 1986, pp. 114-117.
Klausner, A., "Monoclonal Makers Upping Production, Vying for New Contracts", Biotech., Nov., 1983, pp. 736-640.
Chemical Abstracts, vol. 79, No. 25, Dec. 24, 1973 (Columbus, Ohio) p. 218, Abstract 145072r, & JP, A, 7316183 (Snow Brand Milk Products Co., Ltd.) May 19, 1973.
Biotechnology and Bioengineering, vol. 27, No. 2, Feb., 1985, .+-. John Willey & Sons, Inc. (New York) Goosen, M. F. A. et al.: "Optimization of microencapsulation parameters: semipermeable microcapsules as a bio-artificial pancreas", pp. 146-150, pp. 146-147, Materials and methods. Microencapsulatio of living cells; p. 147, Dependence of microcapsule morphology on sodium alginate viscosity and purity.
Spiekermann, K. D., et al., "Animal Cells Encapsulated Within Ca-Alginate Hollow-Spheres", Proc. 4th Euro. Conf. Biotech., vol. 3, Oct. 1, 1987, pp. 590-593.

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