Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1989-11-22
1992-05-26
Lacey, David L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 697, 4352523, 43532011, 530350, C07H 2104, C12N 1562, C12P 2102
Patent
active
051169649
ABSTRACT:
Immunoglobulin fusion polypeptides are provided, together with methods for making and using them, and nucleic acids encoding them. These polypeptides are useful as cell surface adhesion molecules and ligands, and are useful in therapeutic or diagnostic compositions and methods.
REFERENCES:
Nature, vol. 331; pp. 84-86, Jan. 7, 1988, Traunecker et al., Soluble CD4 Molecules Neutralize Human Immunodeficiency Virus Type 1.
Eur. J. Immunol., 16; pp. 851-854, 1986, Traunecker et al., A Novel Approach for Preparing Anti-T-Cell Receptor Constant Region Antibodies.
Nature, vol. 312; pp. 605-608, Dec. 13, 1984, Neuberger et al., Recombinant Antibodies Possessing Novel Effector Functions.
P.N.A.S., vol. 84, pp. 2936-2940, May, 1987, Gascoigne et al., Secretion of a Chimeric T-Cell Receptor-Immunoglobulin Protein.
Gene, 43:319-324, 1986, Williams et al., Production of Antibody-Tagged Enzymes by Myeloma Cells: Application to DNA Polymerase I Klenow Fragment.
Cell, 58:911-921, Sep. 8, 1989, Becker et al., Expression of a Hybrid Immunoglobulin-T Cell Receptor Protein in Transgenic Mice.
J. of Biol. Chem., 264:7310-7316, May 5, 1989; Mariuzza et al., Secretion of a Homodimeric V.sub..alpha. C.sub..kappa. T-Cell Receptor-Immunoglobulin Chimeric Protein.
Nature, vol. 337, pp. 525-531, Feb. 9, 1989, Capon et al., Designing CD4 Immunoadhesins for AIDS Therapy.
Nature, vol. 339, pp. 68-70, May 4, 1989, Traunecker et al., Highly Efficient Neutralization of HIV with Recombinant CD4-Immunoglobulin Molecules.
Watson et al., J. Cell. Biochem. Suppl., 0 (14 part B), 84 (1990) (P).
Camerini et al., Letters to Nature, 342, 78-82 (1989) (A).
Bowen et al., J. Cell. Biol., 109, 421-427 (1989) (A).
Siegelman et al., Proc. Natl. Acad. Sci. USA, 86, 5562-5566 (1989) (A).
Reed et al., Chem. Abstr., 109(25) 587 (1988), Abstract 227803g & Clin. Chem., 34, 1992-1994 (1988).
Kikutani et al., Cell, 47, 657-665, (1986).
Eliasson et al., J. Immunol., 142, 575-581 (1989).
Morrison, S. L., Science, 229:1202-1207 (1985).
Capon et al., Nature, 337:525-531 (1989).
Traunecker et al., Nature, 339:68-70 (1989).
Butcher, E. C., Current Topics in Microbiol. and Immunol., 128: Springer-Verlag Berlin-Heidelberg, pp. 85-122 (1986).
Gallatin et al., Cell, 44:673-680 (1986).
Lewinsohn et al., J. Immunology, 138(12):4313-4321 (1987).
Siegelman et al., Science, 231:823-829 (1986).
St. John et al., Science, 231:845-850 (1986).
Jalkanen et al., Eur. J. Immunol., 16:1195-1202 (1986).
Jalkanen et al., J. Cell Biology, 105:983-990 (1987).
Stoolman et al., J. Cell Biology, 99:1535-1540 (1984).
Bischoff, R., J. Cell Biology, 102:2273-2280 (1986).
Bleil & Wassarman, Proc. Natl. Acad. Sci. USA, 85:6778-6782 (1988).
Brandley et al., J. Cell Biology, 105:991-997 (1987).
Crocker & Gordon, J. Exp. Med., 164:1862-1875 (1986).
DeAngelis & Glabe, J. Biol. Chem., 262(29):13946-13952 (1987).
Duijvestijn & Hamann, Immunology Today, 10(1);23-28 (1989).
Fenderson et al., J. Exp. Med., 160:1591-1596 (1984).
Gascoigne et al., Proc. Natl. Acad. Sci. USA, 84:2936-2940 (1987).
Grabel et al., Cell, 17:477-484 (1979).
Jalkanen & Butcher, Blood, 66:577-582 (1985).
Knapp et al., Immunology Today, 10(8):253-258 (1989).
Kunemund et al., J. Cell Biology, 106:213-223 (1988).
Lopez et al., J. Cell. Biology, 101:1501-1510 (1985).
Rasmussen et al., J. Immunology, 135(1);19-24 (1985).
Rosen et al., Science, 228:1005-1007 (1985).
Sharon, N., FEBS Letters, 217(2):145-157 (1987).
Stoolman et al., Blood, 70(6):1842-1850 (1987).
Yednock et al., J. Cell Biology, 104:725-731 (1987).
Munro, A., Nature, 312:597 (1984).
Sharon et al., Nature, 309:364-367 (1984).
Morrison et al., Proc. Natl. Acad. Sci. USA, 81:6851-6855 (1984).
Boullianne et al., Nature, 312:643-646 (1984).
Woodruff et al., Ann. Rev. Immunol., 5:201-222 (1987).
Chin et al., J. Immunol., 136:2556-2561 (1986).
Glabe et al., J. Cell. Biol., 94:123-128 (1982).
Paulson, J. C., The Receptors 2:P. M. Conn, ed., Academic Press, Inc., (1985), pp. 131-219.
Mountz et al., J. Immunol., 140(9):2943-2949 (1988).
Rosen et al., J. Immunol., 142(6):1895-1902 (1989).
Jalkanen et al., Ann. Rev. Med., 38:467-476 (1987).
Yednock & Rosen, Adv. Immunol., 44:313-78 (1989).
Capon Daniel J.
Lasky Laurence A.
Adler Carolyn R.
Dreger Ginger R.
Genentech Inc.
Lacey David L.
Ulm John D.
LandOfFree
Hybrid immunoglobulins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hybrid immunoglobulins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hybrid immunoglobulins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-421116