Hybrid human/animal factor VIII

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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435 696, 4351723, 4241851, 530383, 930100, A61K 3800, C12P 2104, C12N 1500, C07K 14755

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active

057444463

ABSTRACT:
Provided is a hybrid Factor VIII having a sequence of amino acids selected from the group of A2 domain fragments 373-540, 373-508, 445-508, 484-508, 404-508, 489-508 and 484-489 according to Seq ID NO 2 substituted with corresponding sequence of porcine or murine Factor VIII. Invention also relates to methods of treatment Factor VIII deficiency with said hybrid Factor VIII.

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