Hybrid DNA prepared binding composition

Details Hybrid DNA prepared binding composition Hybrid DNA prepared binding composition

1983-12-05

1987-02-10

Schain, Howard E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530389, 530391, 530808, 530809, 435 68, 435 70, 435 91, 4351722, 4351723, 435253, 435317, 435 7, 424 85, A61K 39395

Patent

active

046423346

ABSTRACT:
Proteinaceous binding compositions are prepared employing hybrid DNA techogy, where the variable region polypeptides of immunoglobulins are substantially reproduced to provide relatively small protein molecules having binding specificity and lacking the undesirable aspects of the heavy regions of immunoglobulins. The compositions find a wide range of use, particularly for physiological purposes for diagnosis and therapy. The binding compositions may be modified by labeling with radioisotopes, fluorescers, and toxins for specific applications in diagnosis or therapy.

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