Hybrid cell line formed between T4 lymphocytes and tumoral lymph

Chemistry: molecular biology and microbiology – Spore forming or isolating process

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4352401, 4351721, 4351722, C12N 522

Patent

active

055500528

ABSTRACT:
The invention relates to new purified antigens of the LAV virus. They have molecular weights of about 135,000 and 150,000 daltons. They are useful for the detection of LAV antibodies in human sera. They are produced by hybrid cell-lines resulting from the fusion of T4 lymphocytes and cells of the MOLT-4 cell line.

REFERENCES:
patent: 4591552 (1986-05-01), Neurath
patent: 4629783 (1986-12-01), Cosand
patent: 4665032 (1987-05-01), Laurence
patent: 4675295 (1987-06-01), Osawa et al.
patent: 4725669 (1988-02-01), Essex et al.
Le et al, "Human T cell hybridomas secreting immune interferon", Proceedings of the National Academy of Science, vol. 79, pp. 7857-7861, (Dec. 1982).
Klatzmann et al: "Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes" Science 225 pp. 59-63 (6 Jul. 1984).
Montagnier et al: Identification . . . Associated Virus Virology 144 (1985) 283-89.
Meusing et al "Nucleic Acid Structure and Expression of the Human AIDS/Lymphodenapathy Retrovirus", Nature, 313 (Feb. 7, 1985) 450-458.
Crowl et al, "HTLV-III Env Gene Product Synthesized in E. coli Are Recognized by Antibodies Present in the Sera of AIDS Patients", Cell, 44(Jul. 1985) 979-86.
Ratnes et al, "Complete Nucleotide Sequence of the AIDS Virus, HTLV-III", Nature, 313 (Jan. 24, 1985) 277-83.
Schupbach et al, "Antibodies to HTLV-III in Swiss Patients With AIDS and Pre-AIDS and in Groups at Risk for AIDS", New England J. Med., 312 (Jan. 31, 1985) 265-270.
Sanchez-Pescador et al, "Nucleotide Sequence and Expression of an AIDS-Associated Retrovirus (ARV-2)" Science, 227 (Feb. 1, 1985) 484-92.
Schneider et al, "A. Glycoprotein (Ogp 100) is the Main Antigen Detected by HTLV-III Antisera", Med. Microbiol. Immunol., 174 (1985) 35-42.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hybrid cell line formed between T4 lymphocytes and tumoral lymph does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hybrid cell line formed between T4 lymphocytes and tumoral lymph, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hybrid cell line formed between T4 lymphocytes and tumoral lymph will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1055880

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.