Hybrid cell line for producing monoclonal antibody to human cyto

Details Hybrid cell line for producing monoclonal antibody to human cyto Hybrid cell line for producing monoclonal antibody to human cyto

1982-10-04

1987-01-20

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351722, 435 68, 435948, 935104, 935 92, 935110, C12N 500, C12N 1500, C12P 2100, C12R 191

Patent

active

046379835

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on normal human cytotoxic and suppressor T cells. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

REFERENCES:
patent: 4241044 (1980-12-01), Kim
patent: 4294818 (1981-10-01), McMichael et al.
patent: 4359457 (1982-11-01), Neville, Jr. et al.
patent: 4364932 (1982-12-01), Kung et al.
McMicheal, A. J. et al., "A Human Thymocyte Antigen Defined by a Hybrid Myeloma Monoclonal Antibody", European J. of Immunology, vol. 9, Mar. '79, 205-210.

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