Hybrid cell line for producing monoclonal antibody to antigen on

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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435 68, 43524027, 435948, 436548, 530387, 935104, 935105, 935110, A61K 3900, G01N 33577

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047849517

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

REFERENCES:
Reinherz et al., J. Immunol., vol. 123, 1979, pp. 1312-1317.

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