Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1984-08-31
1990-09-25
Tarcza, J. E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
935104, A61K 39395
Patent
active
049594583
ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on normal human monocytes and granulocytes. The hybrid is formed by fusing splenocytes from immunized BALB/cJ mice with P3X63Ag8Ul myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
REFERENCES:
patent: 4364936 (1982-12-01), Kung et al.
Ugolini et al., "Initial Characterization of Monoclonal Antibodies Against Human Monocytes" Proceedings of the National Academy of Sciences 77(11) pp. 6764-6768 (1980).
Brown et al., "The Distribution of HLA on Human Lymphoid, Bone Marrow and Peripheral Blood Cells" European Journal of Immunology 9, pp. 272-275 (1979).
Goldstein Gideon
Kung Patrick C.
Dellenbaugh Geoffrey G.
Grochala Richard J.
Ortho Pharmaceutical Corporation
Tarcza J. E.
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