Hybrid cell line for producing monoclonal antibody to a human ea

Details Hybrid cell line for producing monoclonal antibody to a human ea Hybrid cell line for producing monoclonal antibody to a human ea

1984-08-09

1987-09-01

Warren, Charles F.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

424 85, 435 68, 43524027, 935104, 530809, A61K 39395, A61K 3516, C12N 500, C12P 2100

Patent

active

046910107

ABSTRACT:
Hybrid cell line for production of monoclonal antibody to an antigen found on approximately 10% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF.sub.1 mice with P3X63Ag8Ul myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

REFERENCES:
patent: 4364934 (1982-12-01), Kung et al.
patent: 4434156 (1984-02-01), Trowbridge

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