Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...
Reexamination Certificate
2007-01-12
2009-10-13
Maier, Leigh C (Department: 1623)
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
C514S061000
Reexamination Certificate
active
07601488
ABSTRACT:
A method for promoting expression of a heat shock protein, or for inhibiting cell injury or cell death, or for treating a disease for which cell or tissue protection is desired, or for promoting production of IL-10, or for inhibiting production of IL-8, by administering an effective amount of a fraction containing a hyaluronic acid tetrasaccharide comprising four saccharide residues and having certain physicochemical properties or by administering an effective amount of an isolated and substantially pure tetrasaccharide of formula (1) described in the application. Methods for preserving an organ.
REFERENCES:
patent: 4141973 (1979-02-01), Balazs
patent: 5902795 (1999-05-01), Toole et al.
patent: 9-227386 (1997-09-01), None
patent: 09-227386 (1997-09-01), None
patent: 11-246301 (1999-09-01), None
patent: 11-310588 (1999-11-01), None
patent: 2000-103738 (2000-04-01), None
patent: 97/37537 (1997-10-01), None
patent: WO 97/37537 (1997-10-01), None
Clavien, P. “Sinusoidal endothelial cell injury during hepatic preservation and reperfusion” Hepatology (1998) vol. 28, No. 2, pp. 281-285.
Roberto Gilli et al., “FTIR Studies of Sodium Hyaluronate And Its Oligomers in the Amorphous Solid Phase and Aqueous Solution,” Carbohydrate Research, vol. 263, pp. 315-326 (1994).
Cowman, M. et al., “Preparation and Circular Dichroism Analysis of Sodium Hyaluronate Oligosaccharides and Chrondroitin,” Biochemistry (1981) vol. 20, No. 5, pp. 1379-1385.
Renato Toffanin et al., NMR Studies of Oligosaccharides Derived from Hyaluronate: Complete Assignment of 1H and 13CNMR Spectra of Aqueous Di- and Tetra-saccharides, and Comparison of Chemical Shifts for Oligosaccharides of Increasing Degree of Polymerisation, Carbohydrate Research, vol. 245 (1993) 113-128.
R. Gilli, et al., “FTIR Studies of Sodium Hyaluronate and its Oligomers in the Amorphous Solid Phase and in Aqueous Solution”, Carbohydrate Research, 1994, vol. 263, pp. 315-326.
P. Bertrand, et al., “Interaction of Hyaluronectin with Hyaluronic Acid Oligosaccharides”, Journal of Neurochemistry, vol. 45, No. 2, 1985, pp. 434-439, XP-000874493.
E. Shimada, et al., “Degradation Process of Hyaluronic Acid”, Journal of Biochemistry, vol. 88, No. 4, 1980, pp. 1015-1023, XP-001032517.
Asari Akira
Kurihara Hitoshi
Masa Takahiro
Matsuzaki Yuji
Miyazaki Yuka
Maier Leigh C
Oblon, Spivak McClelland, Maier & Neustadt, L.L.P.
Seikagaku Corporation
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