Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1993-09-23
1998-11-10
Fonda, Kathleen K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 23, 424493, 536 53, 536 55, 536 551, 536 552, 536 553, A61K 31715, C08B 3700
Patent
active
058344446
ABSTRACT:
A method is provided of preventing arterial restenosis of an animal after the arteries have been traumatized. The method comprises the administration of a therapeutically effective non-toxic amount of hyaluronic acid and/or pharmaceutically acceptable salts thereof to the animal to prevent narrowing of the arteries. The form of hyaluronic acid is selected from hyaluronic acid and pharmaceutically acceptable salts thereof having a molecular weight less than 750,000 daltons.
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Turley, E.A. et al., "Noeintimal formation after balloon catheter injury: a role of hyaluronan and hyaluronan receptor RHAMM", unpublished manuscript submitted by applicant. No months available.
Yang, B. et al., Identfication of two hyaluronan-binding domains in the hyaluronan receptor RHAMM, J. Biol. Chem. vol. 263(12) pp. 8617-8623, 1993 No months available.
Asculai Samuel Simon
Falk Rudolf Edgar
Turley Eva Anne
Fonda Kathleen K.
Hughes Ivor M.
Hughes Neil H.
Hyal Pharmaceutical Corporation
Sarkis Marcelo K.
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