Hyaluronate modified polymeric articles

Details Hyaluronate modified polymeric articles Hyaluronate modified polymeric articles

1983-12-15

1985-02-19

Michl, Paul R.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

424 78, 424 81, 424 82, 424 83, 524 29, C08F 800

Patent

active

045006768

ABSTRACT:
Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered biocompatible by including with the polymeric material hyaluronic acid or a salt thereof. The hyaluronic acid may be coated onto the surface of the polymeric material, dispersed throughout the body of the polymeric material, or both. The hyaluronic acid on the surface of the polymeric material may optionally be cross-linked. The biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves, intraocular lenses, vascular grafts, pacemaker leads and the like.

REFERENCES:
patent: 4272522 (1981-06-01), Balazs
patent: 4349467 (1982-09-01), Williams
patent: 4415490 (1983-11-01), Joh

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