Hyaluronan synthase genes and expression thereof in bacillus...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S101000, C435S252310, C536S053000

Reexamination Certificate

active

06951743

ABSTRACT:
The present invention relates to a recombinantBacillushost cell containing a recombinant vector including a nucleic acid segment having a coding region segment encoding enzymatically active hyaluronan synthase (HAS). The recombinantBacillushost cell is utilized in a method for producing hyaluronic acid (HA).

REFERENCES:
patent: 4224179 (1980-09-01), Schneider
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4511478 (1985-04-01), Nowinski et al.
patent: 4517295 (1985-05-01), Bracke et al.
patent: 4708861 (1987-11-01), Popescu et al.
patent: 4780414 (1988-10-01), Nimrod et al.
patent: 4782046 (1988-11-01), Brown et al.
patent: 4784990 (1988-11-01), Nimrod et al.
patent: 4801539 (1989-01-01), Akasaka et al.
patent: 5015577 (1991-05-01), Weigel et al.
patent: 5023175 (1991-06-01), Hosoya et al.
patent: 5071751 (1991-12-01), Morita et al.
patent: 5948900 (1999-09-01), Yother et al.
patent: RE37336 (2001-08-01), Weigel et al.
patent: 6423514 (2002-07-01), Briskin
patent: 6455304 (2002-09-01), Weigel et al.
patent: 6492150 (2002-12-01), McDonald
patent: 0195303 (1989-11-01), None
patent: 0144019 (1990-06-01), None
patent: 0266578 (1993-07-01), None
patent: 0244757 (1994-11-01), None
patent: 0036776 (1998-05-01), None
patent: 2249315 (1992-05-01), None
patent: 62032893 (1987-07-01), None
patent: 63094988 (1988-04-01), None
patent: 4-158796 (1992-06-01), None
patent: 91/03559 (1991-03-01), None
patent: 94/00463 (1994-01-01), None
patent: 95/24497 (1995-09-01), None
patent: 95/33067 (1995-12-01), None
patent: 97/20061 (1997-06-01), None
Meyer et al., “The Polysaccharide of the Vitreous Humor,” J. Biol. Chem., vol. 107, pp. 629-634, 1934.
DeAngelis et al., “Isolation of aStreptococcus pyogenesGene Locus That Directs Hyaluronan Biosynthesis in Acapsular Mutants and in Heterologous Bacteria,” J. Biol. Chem., vol. 268, No. 20, Jul. 15, 1993, pp. 14568-14571.
DeAngelis et al., “Molecular Cloning, Identification, and Sequence of the Hyaluronan Synthase Gene from Group AStreptococcus pyogenes,” J. Biol. Chem., vol. 268, No. 26, Sep. 15, 1993, pp. 19181-19184.
“The Combinations of Haemoglobin with Oxygen and with Carbon Monoxide.”, Hill, J. Biochem., 7:471-480 (1913).
“The Role of the Mucoid Polysaccharide (Hyaluronic Acid) in the Virulence of Group A Hemolytic Streptococci”, Kass et al., J. Of Exp. Med., 79:319-330 (1944).
“The Production of Capsules, Hyaluronic Acid and Hyaluronidase by Group A and Group C Streptocooci”, MacLennan, J. Gen. Microbiol., 14:134-142 (1956).
“The Isolation and Characterization of a Hyaluronidase Produced by a Capsulated Strain of Group C Streptococcus”, MacLennan, J. Gen. Microbiol., 14:143-152 (1956).
“The Biosynthesis of Hyaluronic Acid by Group A Streptococcus”, Markovitz et al., J. Biol. Chem., 234 (9):2343-2350 (1959).
“The Biosynthesis of Hyaluronic Acid by Streptococcus,” Stoolmiller, et al., Journal of Biological Chemistry, vol. 244, No. 2, pp. 236-246 (1969).
“Cleavage of Structural Proteins During the Assembly of the Head of Bacteriophage T4”, Laemmli, Nature, 227:680-685 (1970).
“The Isolation and Characterization of Hyaluronic Acid from Pasteurella Multocida”, Cifonelli, et al., Carbohydrate Research, 14, 272-276, (1970).
“A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding”, Bradford, Analytical Biochemistry, 72:248-254 (1976).
“Synthesis and Assembly of the Membrane Proteins inE. Coli”,Ito et al., Cell, 11:551-559 (1977).
“Electrophoretic Transfer of Proteins from Polyacrylamide Gels to Nitrocellulose Sheets: Procedure and Some Applications”, Biochemistry, 76: 4350-4354 (1979).
“Biosynthesis of Hyaluronic Acid by Streptococcus”, Sugahara et al., J. Biol. Chem., 254:6252-6261 (1979).
“Modern Genetics”, Ayala, et al., Benjamin/Cummings Publishing Col., Menlo Park CA, p. 45 (1980).
“Hyaluronidase Production by Type B Pasteurella Multocida from Cases of Hemorrhagic Septicemia”, Carter, et al., Journal of Clinical Microbiology, p. 94-96, (1980).
“Hyaluronate Capsule Prevents Attachment of Group A Streptococci to Mouse Peritoneal Macrophages”, Whitnack et al., Infection and Immunity, 31(3):985-991 (1981).
“Strains ofEscherichia ColiCarrying the Structural Gene for Histidyl-tRNA Synthetase on a High Copy-Number Plasmid”, Eisenbels, et al., Mol. Gen. Genet. 183:115-122 (1981).
“Synthesis of Hyaluronate in Differentiated Teratocarcinoma Cells,” Preham, et al., J. Biochem, vol. 211, pp. 181-189 (1983).
“Streptococcal Hyaluronic Acid: Proposed Mechanisms of Degradation and Loss of Synthesis During Stationary Phase”, Van de Rijn, J. Bacteriol., 156(3):1059-1065 (1983).
“Hyaluronate is Synthesized at Plasma Membranes”, Prehm, Biochem. J., 220:597-600 (1984).
“Subcellular Localization of Hyaluronate Synthase in Oligodendroglioma Cells”, Phillipson et al., J. Biol. Chem., 259(8):5017-5023 (1984).
“Solubilization of Hyaluronic Acid Synthetic Activity from Streptococci and Its Activation with Phospholipids”, Triscott et al., J. Biol. Chem., 261(13):6004-6009 (1986).
“Isolation of Streptococcal Hyaluronate Synthase”, Prehm et al., Biochem. J., 235:887-889 (1986).
“Isolation, Structure and Expression of Mammalian Genes for Histidyl-tRNA Synthetase,” Tsul, et al., Nucleic Acids Research, vol. 15, No. 8, pp. 3349-3367, (1987).
“Role of Cysteine Residues in Glutathione Synthase fromEscherichia ColiB”, Kato et al., J. Biol. Chem., 263(24):11646-11651 (1988).
“The Biology of Hyaluronan”, Evered and Whelan Eds., CIBA Foundation Symposium 143 (1989).
“The Role of Bacterial Polysaccharide Capsules as Virulence Factors”, Moxon et al., Current Topics in Microbiology and Immunology, 150:65-85 (1990).
“Hyaluronic Acid Capsule is a Virulence Factor for Mucoid Group A Streptococci”, Wessels et al., Microbiology, 88:8317-8321 (1991).
“Shuttle Vectors Containing a Multiple Cloning Site and a Lacza Gene for Conjugal Transfer of DNA fromEscherichia Colito Gram-Positive Bacteria,” Trieu-Cout, et al., Gene, vol. 102, pp. 99-104, (1991).
“Analysis of the Streptococcal Hyaluronic Acid Synthase Complex Using the Photoaffinity Probe 5-Azido-UDP-Glucuronic Acid,” Van de Rijn, et al., J. Biol., Chem., vol. 267, No. 34, pp. 24302-24306, (1992).
“Molecular Characterization of a Locus Required for Hyaluronic Acid Capsule Production in Group A Streptococci,” Dougherty, et al., J. Exp. Med., vol. 175, pp. 1291-1299, (1992).
“Hyaluronan,” Laurent, et al., FASEB Journal, vol. 6, pp. 2397-2404, (1992).
“Role of Cysteins 640, 656, and 661 in Steroid Binding to Rat Glucocorticoid Receptors”, Chakraborti et al., J. Biol. Chem., 267(16):11366-11373 (1992).
“Hyaluronic Acid and A (1-4)-B-D-Xylan, Extracellular Polysaccharides of Pasteurella Multocida (Carter Type A) Strain 880”, Rosner, et al., Carbohydrate Research, 223, 329-333 (1992).
“Localization of Hyaluronan in Mouse Embryos During Implantation, Gastrulation and Organogenesis”, Fenderson et al., Differentiation, 54:85-98 (1993).
“Hyaluronan-Binding Proteins in Development, Tissue Homeostasis, and Disease”, Knudson et al., FASEB, 7:1233-1241 (1993).
“Molecular Cloning, Identification, and Sequence of the Hyaluronan Synthase Gene from Group AStreptococcus Pyogenes”, DeAngelis et al., J. Biol. Chem., 268(26):19181-19184 (1993).
“Isolation of aStreptococcus PyogenesGene Locus that Directs Hyaluronan Biosynthesis in Acapsular Mutants and in Heterologous Bacteria,” DeAngelis, et al., J. Biol. Chem., vol. 268, No. 20, pp. 14568-14571, (1993).
“Hyaluronate Synthase: Cloning and Sequencing of the Gene from Strep

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hyaluronan synthase genes and expression thereof in bacillus... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hyaluronan synthase genes and expression thereof in bacillus..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hyaluronan synthase genes and expression thereof in bacillus... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3472332

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.