Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1990-04-25
1992-02-11
Doll, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 75, 530324, 530325, 514 12, 436501, 930290, 930DIG820, G01N 33567, C07K 710, A61K 3724
Patent
active
050875620
ABSTRACT:
The present invention relates to the use of peptide analogues as inhibitors of their respective naturally occurring peptides. The structure of the peptide hormone analogues is exemplified by human humoral hypercalcemic factor (hHCF), wherein Lys.sup.13 is modified so as to produce HCF analogues which can inhibit the action of HCF.
REFERENCES:
Juppner et al., Biochemistry, vol. 29 (30), pp. 6941-6, ()1990).apprxeq.Chem. Abs. 113(15), 126872f.
Coltrera et al., American Chem. Society, vol. 19, No. 18, pp. 4380-4384, (1980).
The Merck Manual, 11th ed., (1966), pp. 452-53.
Chorev Michael
Nutt Ruth F.
Rosenblatt Michael
Roubini Eliahu
Caruso Charles M.
Doll John
Merck & Co. , Inc.
Mitri Salvatore C.
Wissendorf T.
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