Humanized polynucleotide sequence encoding Renilla mulleri...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

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C435S243000, C435S320100, C435S419000, C536S023500

Reexamination Certificate

active

06884620

ABSTRACT:
The present invention provides a polynucleotide encoding a green fluorescent protein fromRenilla mullericomprising a humanized sequence which permits enhanced expression of the encoded polypeptide in mammalian cells.

REFERENCES:
patent: 5968750 (1999-10-01), Zolotukhin et al.
patent: 6232107 (2001-05-01), Bryan et al.
patent: WO 9949019 (1999-09-01), None
patent: WO 0168824 (2001-09-01), None
Felts, K. et al.; (2000), “Vitality™ hrGFP Displays Low Toxicity”,Strategies, 13:85-87.
International Search Report of International Application No. PCT/US01/49091.

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